diff --git a/.github/workflows/main.yml b/.github/workflows/main.yml
index 47040d01..2cf9ec99 100644
--- a/.github/workflows/main.yml
+++ b/.github/workflows/main.yml
@@ -192,6 +192,49 @@ jobs:
       - run: cargo test --no-run --target ${{ matrix.target }} --release
       - run: cargo test --no-run --target ${{ matrix.target }} --features parallel
 
+  test-wasm32-wasip1-thread:
+    name: Test wasm32-wasip1-thread
+    runs-on: ubuntu-latest
+    env:
+      TARGET: wasm32-wasip1-threads
+    steps:
+      - uses: actions/checkout@v4
+      - name: Install Rust (rustup)
+        run: |
+          rustup toolchain install nightly --no-self-update --profile minimal --target $TARGET
+
+      - name: Get latest version of wasi-sdk
+        env:
+          REPO: WebAssembly/wasi-sdk
+          GH_TOKEN: ${{ github.token }}
+        run: |
+          set -euxo pipefail
+          VERSION="$(gh release list --repo $REPO -L 1 --json tagName --jq '.[]|.tagName')"
+          echo "WASI_TOOLCHAIN_VERSION=$VERSION" >> "$GITHUB_ENV"
+
+      - name: Install wasi-sdk
+        working-directory: /tmp
+        env:
+          REPO: WebAssembly/wasi-sdk
+        run: |
+          set -euxo pipefail
+          VERSION="$WASI_TOOLCHAIN_VERSION"
+          FILE="${VERSION}.0-x86_64-linux.deb"
+          wget "https://github.com/$REPO/releases/download/${VERSION}/${FILE}"
+          sudo dpkg -i "${FILE}"
+          WASI_SDK_PATH="/opt/wasi-sdk"
+          CC="${WASI_SDK_PATH}/bin/clang"
+          echo "WASI_SDK_PATH=$WASI_SDK_PATH" >> "$GITHUB_ENV"
+          echo "CC=$CC" >> "$GITHUB_ENV"
+
+      - uses: Swatinem/rust-cache@v2
+        with:
+          env-vars: "WASI_TOOLCHAIN_VERSION"
+          cache-all-crates: "true"
+
+      - name: Run tests
+        run: cargo +nightly build -p $TARGET-test --target $TARGET
+
   cuda:
     name: Test CUDA support
     runs-on: ubuntu-20.04
diff --git a/Cargo.toml b/Cargo.toml
index d287d36c..b2054998 100644
--- a/Cargo.toml
+++ b/Cargo.toml
@@ -42,4 +42,8 @@ members = [
     "dev-tools/cc-test",
     "dev-tools/gen-target-info",
     "dev-tools/gen-windows-sys-binding",
+    "dev-tools/wasm32-wasip1-threads-test",
 ]
+
+[patch.crates-io]
+cc = { path = "." }
diff --git a/dev-tools/wasm32-wasip1-threads-test/Cargo.toml b/dev-tools/wasm32-wasip1-threads-test/Cargo.toml
new file mode 100644
index 00000000..9308ecab
--- /dev/null
+++ b/dev-tools/wasm32-wasip1-threads-test/Cargo.toml
@@ -0,0 +1,8 @@
+[package]
+name = "wasm32-wasip1-threads-test"
+version = "0.1.0"
+edition = "2021"
+publish = false
+
+[dependencies]
+rusqlite = { version = "0.32.0", features = ["bundled"] }
diff --git a/dev-tools/wasm32-wasip1-threads-test/src/main.rs b/dev-tools/wasm32-wasip1-threads-test/src/main.rs
new file mode 100644
index 00000000..0181b84d
--- /dev/null
+++ b/dev-tools/wasm32-wasip1-threads-test/src/main.rs
@@ -0,0 +1,44 @@
+use rusqlite::{Connection, Result};
+
+#[derive(Debug)]
+struct Person {
+    pub id: i32,
+    pub name: String,
+    pub data: Option<Vec<u8>>,
+}
+
+fn main() -> Result<()> {
+    let conn = Connection::open_in_memory()?;
+
+    conn.execute(
+        "CREATE TABLE person (
+            id    INTEGER PRIMARY KEY,
+            name  TEXT NOT NULL,
+            data  BLOB
+        )",
+        (), // empty list of parameters.
+    )?;
+    let me = Person {
+        id: 0,
+        name: "Steven".to_string(),
+        data: None,
+    };
+    conn.execute(
+        "INSERT INTO person (name, data) VALUES (?1, ?2)",
+        (&me.name, &me.data),
+    )?;
+
+    let mut stmt = conn.prepare("SELECT id, name, data FROM person")?;
+    let person_iter = stmt.query_map([], |row| {
+        Ok(Person {
+            id: row.get(0)?,
+            name: row.get(1)?,
+            data: row.get(2)?,
+        })
+    })?;
+
+    for person in person_iter {
+        println!("Found person {:?}", person.unwrap());
+    }
+    Ok(())
+}
diff --git a/src/lib.rs b/src/lib.rs
index deda67e5..0b2333b6 100644
--- a/src/lib.rs
+++ b/src/lib.rs
@@ -2019,6 +2019,10 @@ impl Build {
                             format!("--sysroot={}", Path::new(&wasi_sysroot).display()).into(),
                         );
                     }
+
+                    if target.contains("threads") {
+                        cmd.push_cc_arg("-pthread".into());
+                    }
                 }
             }
         }